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In science there is and will remain a Platonic element which could not be taken away without ruining it. Among the infinite diversity of singular phenomena science can only look for invariants.
Jacques Monod
My laboratory is interested in the related challenges of understanding the origin of life on the early earth, and constructing synthetic cellular life in the laboratory. Focusing on artificial life frees us to explore novel chemical systems, but what we learn from these systems helps us to understand possible pathways leading to the origin of life. Our basic design for a synthetic cell involves the encapsulation of a spontaneously replicating nucleic acid, which acts as the genetic material, within a spontaneously replicating membrane vesicle, which provides spatial localization. We are using chemical synthesis to make nucleic acids with modified nucleobases and sugar-phosphate backbones.
Jack W. Szostak
A DNA sequence for the genome of bacteriophage ΦX174 of approximately 5,375 nucleotides has been determined using the rapid and simple 'plus and minus' method. The sequence identifies many of the features responsible for the production of the proteins of the nine known genes of the organism, including initiation and termination sites for the proteins and RNAs. Two pairs of genes are coded by the same region of DNA using different reading frames.
Frederick Sanger
I would not be among you to-night (being awarded the 1964 Nobel Prize in Physiology or Medicine) but for the mentors, colleagues and students who have guided and aided me throughout my scientific life. I wish I could name them all and tell you their contributions. More, however, than anyone else it was the late Rudolf Schoenheimer, a brilliant scholar and a man of infectious enthusiasm, who introduced me to the wonders of Biochemistry. Ever since, I have been happy to have chosen science as my career, and, to borrow a phrase of Jacques Barzun, have felt that 'Science is, in the best and strictest sense, glorious entertainment'.
Konrad Bloch
The history of atomism is one of reductionism – the effort to reduce all the operations of nature to a small number of laws governing a small number of primordial objects.
Leon M. Lederman
Tapestries are made by many artisans working together. The contributions of separate workers cannot be discerned in the completed work, and the loose and false threads have been covered over. So it is in our picture of particle physics.
Sheldon L. Glashow
It has today occurred to me that an amplifier using semiconductors rather than vacuum is in principle possible.[Laboratory notebook, 29 Dec 1939.]
William Shockley
[Concerning] phosphorescent bodies, and in particular to uranium salts whose phosphorescence has a very brief duration. With the double sulfate of uranium and potassium ... I was able to perform the following experiment: One wraps a Lumière photographic plate with a bromide emulsion in two sheets of very thick black paper, such that the plate does not become clouded upon being exposed to the sun for a day. One places on the sheet of paper, on the outside, a slab of the phosphorescent substance, and one exposes the whole to the sun for several hours. When one then develops the photographic plate, one recognizes that the silhouette of the phosphorescent substance appears in black on the negative. If one places between the phosphorescent substance and the paper a piece of money or a metal screen pierced with a cut-out design, one sees the image of these objects appear on the negative. One can repeat the same experiments placing a thin pane of glass between the phosphorescent substance and the paper, which excludes the possibility of chemical action due to vapors which might emanate from the substance when heated by the sun's rays. One must conclude from these experiments that the phosphorescent substance in question emits rays which pass through the opaque paper and reduces silver
Henri Becquerel
While it is never safe to affirm that the future of Physical Science has no marvels in store even more astonishing than those of the past, it seems probable that most of the grand underlying principles have been firmly established and that further advances are to be sought chiefly in the rigorous application of these principles to all the phenomena which come under our notice.
Robert S. Mulliken
Scientific truth is universal, because it is only discovered by the human brain and not made by it, as art is.
Konrad Lorenz
If the militarily most powerful and least threatened states need nuclear weapons for their security, how can one deny such security to countries that are truly insecure? The present nuclear policy is a recipe for proliferation. It is a policy for disaster.
Joseph Rotblat
I am not religious in any sense; in fact, I consider myself an atheist.
Subrahmanijan Chandrasekhar
But every day I go to work I'm making a bet that the universe is simple, symmetric, and aesthetically pleasing—a universe that we humans, with our limited perspective, will someday understand.
George Smoot
...the scientific attitude implies what I call the postulate of objectivity—that is to say, the fundamental postulate that there is no plan, that there is no intention in the universe. Now, this is basically incompatible with virtually all the religious or metaphysical systems whatever, all of which try to show that there is some sort of harmony between man and the universe and that man is a product—predictable if not indispensable—of the evolution of the universe.
Jacques Monod
[My study of the universe] leaves little doubt that life has occurred on other planets. I doubt if the human race is the most intelligent form of life.
Harold Urey
As chemists, we must rename [our] scheme and insert the symbols Ba, La, Ce in place of Ra, Ac, Th. As nuclear chemists closely associated with physics, we cannot yet convince ourselves to make this leap, which contradicts all previous experience in nuclear physics.
Otto Hahn
Should the research worker of the future discover some means of releasing this [atomic] energy in a form which could be employed, the human race will have at its command powers beyond the dream of scientific fiction, but the remotest possibility must always be considered that the energy once liberated will be completely uncontrollable and by its intense violence detonate all neighbouring substances. In this event, the whole of the hydrogen on earth might be transformed at once and the success of the experiment published at large to the universe as a new star.
Francis William Aston
Is the purpose of theoretical physics to be no more than a cataloging of all the things that can happen when particles interact with each other and separate? Or is it to be an understanding at a deeper level in which there are things that are not directly observable (as the underlying quantized fields are) but in terms of which we shall have a more fundamental understanding?
Julian Schwinger
To me, science is an expression of the human spirit, which reaches every sphere of human culture. It gives an aim and meaning to existence as well as a knowledge, understanding, love, and admiration for the world. It gives a deeper meaning to morality and another dimension to esthetics.
Isidor Isaac Rabi
Unless social sciences can be as creative as natural science, our new tools are not likely to be of much use to us.
Edgar Douglas Adrian
The humanitarian philosophies that have been developed (sometimes under some religious banner and invariably in the face of religious opposition) are human inventions, as the name implies - and our species deserves the credit. I am a devout atheist - nothing else makes any sense to me and I must admit to being bewildered by those, who in the face of what appears so obvious, still believe in a mystical creator. However I can see that the promise of infinite immortality is a more palatable proposition than the absolute certainty of finite mortality which those of us who are subject to free thought (as opposed to free will) have to look forward to and many may not have the strength of character to accept it.Thus I am a supporter of Amnesty International, a humanist and an atheist. I believe in a secular, democratic society in which women and men have total equality, and individuals can pursue their lives as they wish, free of constraints - religious or otherwise. I feel that the difficult ethical and social problems which invariably arise must be solved, as best they can, by discussion and am opposed to the crude simplistic application of dogmatic rules invented in past millennia and ascribed to a plethora of mystical creators - or the latest invention; a single creator masquerading under a plethora of pseudonyms. Organisations which seek political influence by co-ordinated effort disturb me and thus I believe religious and related pressure groups which operate in this way are acting antidemocratically and should play no part in politics. I also have problems with those who preach racist and related ideologies which seem almost indistinguishable from nationalism, patriotism and religious conviction.
Harry W. Kroto
I told my three sons stories about germs more than fifty years ago as fanciful bedtime tales.
Arthur Kornberg
I cannot understand why we idle discussing religion. If we are honest—and scientists have to be—we must admit that religion is a jumble of false assertions, with no basis in reality. The very idea of God is a product of the human imagination. It is quite understandable why primitive people, who were so much more exposed to the overpowering forces of nature than we are today, should have personified these forces in fear and trembling. But nowadays, when we understand so many natural processes, we have no need for such solutions. I can't for the life of me see how the postulate of an Almighty God helps us in any way. What I do see is that this assumption leads to such unproductive questions as why God allows so much misery and injustice, the exploitation of the poor by the rich and all the other horrors He might have prevented. If religion is still being taught, it is by no means because its ideas still convince us, but simply because some of us want to keep the lower classes quiet. Quiet people are much easier to govern than clamorous and dissatisfied ones. They are also much easier to exploit. Religion is a kind of opium that allows a nation to lull itself into wishful dreams and so forget the injustices that are being perpetrated against the people. Hence the close alliance between those two great political forces, the State and the Church. Both need the illusion that a kindly God rewards—in heaven if not on earth—all those who have not risen up against injustice, who have done their duty quietly and uncomplainingly. That is precisely why the honest assertion that God is a mere product of the human imagination is branded as the worst of all mortal sins.
Paul A.M. Dirac
It was quite the most incredible event that has ever happened to me in my life. It was almost as incredible as if you fired a 15-inch shell at a piece of tissue paper and it came back and hi
Ernest Rutherford
It was quite the most incredible event that has ever happened to me in my life. It was almost as incredible as if you fired a 15-inch shell at a piece of tissue paper and it came back and hi
Ernest Rutherford
Not only are there meaningless questions, but many of the problems with which the human intellect has tortured itself turn out to be only 'pseudo problems,' because they can be formulated only in terms of questions which are meaningless. Many of the traditional problems of philosophy, of religion, or of ethics, are of this character. Consider, for example, the problem of the freedom of the will. You maintain that you are free to take either the right- or the left-hand fork in the road. I defy you to set up a single objective criterion by which you can prove after you have made the turn that you might have made the other. The problem has no meaning in the sphere of objective activity; it only relates to my personal subjective feelings while making the decision.
Percy Williams Bridgman
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