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As long as museums and universities send out expeditions to bring to light new forms of living and extinct animals and new data illustrating the interrelations of organisms and their environments, as long as anatomists desire a broad comparative basis human for anatomy, as long as even a few students feel a strong curiosity to learn about the course of evolution and relationships of animals, the old problems of taxonomy, phylogeny and evolution will gradually reassert themselves even in competition with brilliant and highly fruitful laboratory studies in cytology, genetics and physiological chemistry.
William King Gregory
I'm doing now with cornets exactly what I used to do with trilobites: measuring, analyzing and cataloging the myriad gradations of their forms.
Niles Eldredge
More about the selection theory: Jerne meant that the Socratic idea of learning was a fitting analogy for 'the logical basis of the selective theories of antibody formation': Can the truth (the capability to synthesize an antibody) be learned? If so, it must be assumed not to pre-exist; to be learned, it must be acquired. We are thus confronted with the difficulty to which Socrates calls attention in Meno [ ... ] namely, that it makes as little sense to search for what one does not know as to search for what one knows; what one knows, one cannot search for, since one knows it already, and what one does not know, one cannot search for, since one does not even know what to search for. Socrates resolves this difficulty by postulating that learning is nothing but recollection. The truth (the capability to synthesize an antibody) cannot be brought in, but was already inherent.
Niels Kaj Jerne
An example of such emergent phenomena is the origin of life from non-living chemical compounds in the oldest, lifeless oceans of the earth. Here, aided by the radiation energy received from the sun, countless chemical materials were synthesized and accumulated in such a way that they constituted, as it were, a primeval “soup.” In this primeval soup, by infinite variations of lifeless growth and decay of substances during some billions of years, the way of life was ultimately reached, with its metabolism characterized by selective assimilation and dissimilation as end stations of a sluiced and canalized flow of free chemical energy.
R.W. van Bemmelen
This view, as a rounded whole and in all its essential elements, has very recently disappeared from science. It died a royal death with Agassiz.[It had formerly been held that there were no genetic connections among species.]
Asa Gray
For in disease the most voluntary or most special movements, faculties, etc., suffer first and most, that is in an order the exact opposite of evolution. Therefore I call this the principle of Dissolution.
John Hughlings Jackson
Every day, hundreds of observations and experiments pour into the hopper of the scientific literature. Many of them don't have much to do with evolution - they're observations about the details of physiology, biochemistry, development, and so on - but many of them do. And every fact that has something to do with evolution confirms its truth. Every fossil that we find, every DNA molecule that we sequence, every organ system that we dissect, supports the idea that species evolved from common ancestors. Despite innumerable possible observations that could prove evolution untrue, we don't have a single one. We don't find mammals in Precambrian rocks, humans in the same layers as dinosaurs, or any other fossils out of evolutionary order. DNA sequencing supports the evolutionary relationships of species originally deduced from the fossil record. And, as natural selection predicts, we find no species with adaptations that only benefit a different species. We do find dead genes and vestigial organs, incomprehensible under the idea of special creation. Despite a million chances to be wrong, evolution always comes up right. That is as close as we can get to a scientific truth.
Jerry A. Coyne
Natural selection is a mechanism for generating an exceedingly high degree of improbability.
Ronald A. Fisher
The tendency to variation in living beings, which all admitted as a matter of fact; the selective influence of conditions, which no one could deny to be a matter of fact, when his attention was drawn to the evidence; and the occurrence of great geological changes which also was matter of fact; could be used as the only necessary postulates of a theory of the evolution of plants and animals which, even if not at once, competent to explain all the known facts of biological science, could not be shown to be inconsistent with any.
Thomas Henry Huxley
The fundamental biological variant is DNA. That is why Mendel's definition of the gene as the unvarying bearer of hereditary traits, its chemical identification by Avery (confirmed by Hershey), and the elucidation by Watson and Crick of the structural basis of its replicative invariance, are without any doubt the most important discoveries ever made in biology. To this must be added the theory of natural selection, whose certainty and full significance were established only by those later theories.
Jacques Monod
The occurrence of successive forms of life upon our globe is an historical fact, which cannot be disputed; and the relation of these successive forms, as stages of evolution of the same type, is established in various cases.
Thomas Henry Huxley
When one ponders on the tremendous journey of evolution over the past three billion years or so, the prodigious wealth of structures it has engendered, and the extraordinarily effective teleonomic performances of living beings from bacteria to man, one may well find oneself beginning to doubt again whether all this could conceivably be the product of an enormous lottery presided over by natural selection, blindly picking the rare winners from among numbers drawn at random. [Nevertheless,] a detailed review of the accumulated modern evidence [shows] that this conception alone is compatible with the facts.
Jacques Monod
Even today a good many distinguished minds seem unable to accept or even to understand that from a source of noise natural selection alone and unaided could have drawn all the music of the biosphere. In effect natural selection operates upon the products of chance and can feed nowhere else; but it operates in a domain of very demanding conditions, and from this domain chance is barred. It is not to chance but to these conditions that evolution owes its generally progressive course, its successive conquests, and the impression it gives of a smooth and steady unfolding.
Jacques Monod
An irrefutable proof that such single-celled primaeval animals really existed as the direct ancestors of Man, is furnished according to the fundamental law of biogeny by the fact that the human egg is nothing more than a simple cell.
Ernst Haeckel
The ancestors of the higher animals must be regarded as one-celled beings, similar to the Amoebae which at the present day occur in our rivers, pools, and lakes. The incontrovertible fact that each human individual develops from an egg, which, in common with those of all animals, is a simple cell, most clearly proves that the most remote ancestors of man were primordial animals of this sort, of a form equivalent to a simple cell. When, therefore, the theory of the animal descent of man is condemned as a 'horrible, shocking, and immoral' doctrine, tho unalterable fact, which can be proved at any moment under the microscope, that the human egg is a simple cell, which is in no way different to those of other mammals, must equally be pronounced 'horrible, shocking, and immoral.
Ernst Haeckel
Black magic, the magic of the primeval chaos, blots out or transmogrifies the true form of things. At the stroke of twelve the princess must flee the banquet or risk discovery in the rags of a kitchen wench; coach reverts to pumpkin. Instability lies at the heart of the world. With uncanny foresight folklore has long toyed symbolically with what the nineteenth century was to proclaim a reality - namely, that form is an illusion of the time dimension, that the magic flight of the pursued hero or heroine through frogskin and wolf coat has been, and will continue to be, the flight of all men.
Loren Eiseley
The practice of that which is ethically best—what we call goodness or virtue—involves a course of conduct which, in all respects, is opposed to that which leads to success in the cosmic struggle for existence. In place of ruthless self-assertion it demands self-restraint; in place of thrusting aside, or treading down, all competitors, it requires that the individual shall not merely respect, but shall help his fellows... It repudiates the gladiatorial theory of existence... Laws and moral precepts are directed to the end of curbing the cosmic process.
Thomas Henry Huxley
Few scientists acquainted with the chemistry of biological systems at the molecular level can avoid being inspired. Evolution has produced chemical compounds exquisitely organized to accomplish the most complicated and delicate of tasks. Many organic chemists viewing crystal structures of enzyme systems or nucleic acids and knowing the marvels of specificity of the immune systems must dream of designing and synthesizing simpler organic compounds that imitate working features of these naturally occurring compounds.
Donald J. Cram
The question of the position of man, as an animal, has given rise to much disputation, with the result of proving that there is no anatomical or developmental character by which he is more widely distinguished from the group of animals most nearly allied to him, than they are from one another.
Thomas Henry Huxley
There can be no doubt that the existing Fauna and Flora is but the last term of a long series of equally numerous contemporary species, which have succeeded one another, by the slow and gradual substitution of species for species, in the vast interval of time which has elapsed between the deposition of the earliest fossiliferous strata and the present day.
Thomas Henry Huxley
All organisms vary. It is in the highest degree improbable that any given variety should have exactly the same relations to surrounding conditions as the parent stock. In that case it is either better fitted (when the variation may be called useful), or worse fitted, to cope with them. If better, it will tend to supplant the parent stock; if worse, it will tend to be extinguished by the parent stock.If (as is hardly conceivable) the new variety is so perfectly adapted to the conditions that no improvement upon it is possible,—it will persist, because, though it does not cease to vary, the varieties will be inferior to itself.If, as is more probable, the new variety is by no means perfectly adapted to its conditions, but only fairly well adapted to them, it will persist, so long as none of the varieties which it throws off are better adapted than itself.On the other hand, as soon as it varies in a useful way, i.e. when the variation is such as to adapt it more perfectly to its conditions, the fresh variety will tend to supplant the former.
Thomas Henry Huxley
The platypus, as it turns out, derives its DNA from a menagerie of creatures. When its genome was fully decoded, it was found only to be 80% mammalian, and had genes found previously only in reptilian, bird, amphibian, and fish DNA.
B.C. Chase
Now the leatherback turtle overcame the heat issue via a simple, but evolutionarily impossible solution; it is the only reptile that possesses fatty insulation known as brown adipose tissue, and the only reptile that regulates a high body temperature. This brown adipose tissue is the expression of the UCP1 gene, and, aside from the leatherbacks, is found only in mammals, amphibians, and fishes. Not one other reptile has UCP1.
B.C. Chase
Today, the theory of evolution is an accepted fact for everyone but a fundamentalist minority, whose objections are based not on reasoning but on doctrinaire adherence to religious principles.
James D. Watson
Far from being the smartest possible biological species, we are probably better thought of as the stupidest possible biological species capable of starting a technological civilization - a niche we filled because we got there first, not because we are in any sense optimally adapted to it.
Nick Bostrom
The myosin in our own skeletal muscles is more closely related to the myosin driving the flight muscles of that irritating housefly buzzing around your head than it is to the myosin in the muscles of your own sphincters
Nick Lane
All social animals, including people, live under constant pressure from two competing interests: protecting themselves from others and aligning themselves with others. When these two interests are balanced, the result is dynamic social homeostasis.
Mystery
If about a dozen genera of birds had become extinct or were unknown, who would have ventured to have surmised that birds might have existed which used their wings solely as flappers, like the logger-headed duck (Micropterus of Eyton); as fins in the water and front legs on the land, like the penguin; as sails, like the ostrich; and functionally for no purpose, like the Apteryx. Yet the structure of each of these birds is good for it, under the conditions of life to which it is exposed, for each has to live by a struggle; but it is not necessarily the best possible under all possible conditions. It must not be inferred from these remarks that any of the grades of wing-structure here alluded to, which perhaps may all have resulted from disuse, indicate the natural steps by which birds have acquired their perfect power of flight; but they serve, at least, to show what diversified means of transition are possible.
Charles Darwin
We should not be too quick to dismiss our own [ocular] arrangement. As so often in biology, the situation is more complex.....we have the advantage that our own light-sensitive cells are embedded directly in their support cells (the retinal pigment epithelium) with an excellent blood supply immediately underneath. Such an arrangement supports the continuous turnover of photosensitive pigments. The human retina consumes even more oxygen than the brain, per gram, making it the most energetic organ in the body.
Nick Lane
The idea of decimation as a lottery converts the new iconography of the Burgess Shale into a radical view about the pathways of life and the nature of history. ... May our poor and improbable species find joy in its new-found fragility and good fortune! Wouldn't anyone with the slightest sense of adventure, or the most weakly flickering respect for intellect, gladly exchange the old cosmic comfort for a look at something so weird and wonderful - yet so real - as *Opabinia*?
Stephen Jay Gould
What, after all, is so special about genes? The answer is that they are replicators. The laws of physics are supposed to be true all over the accessible universe. Are there any principles of biology which are likely to have similar universal validity? When astronauts voyage to distant planets and look for life, they can expect to find creatures too strange and unearthly for us to imagine. But is there anything which must be true of all life, wherever it is found, and whatever the basis of its chemistry? If forms of life exist whose chemistry is based on silicon rather than carbon, or ammonia rather than water, if creatures are discovered which boil to death at -100 degrees centigrade, if a form of life is found which is not based on chemistry at all, but on electronic reverberating circuits, will there still be any general principle which is true of all life? Obviously I do not know but, if I had to bet, I would put my money on one fundamental principle. This is the law that all life evolves by the differential survival of replicating entities. The gene, the DNA molecule, happens to be the replicating entity which prevails on our own planet. There may be others. If there are, provided certain conditions are met, they will almost inevitably tend to becometthe basis for an evolutionary process.
Richard Dawkins
The essential quality that an entity needs, if it is to become an effective gene vehicle, is this. It must have an impartial exit channel into the future, for all the genes inside it. This is true of an individual wolf. The channel is the thin stream of sperms, or eggs, which it manufactures by meiosis. It is not true of the pack of wolves. Genes have something to gain from selfishly promoting the welfare of their own individual bodies, at the expense of other genes in the wolf pack. A bee-hive, when it swarms, appears to reproduce by broad-fronted budding, like a wolf pack. But if we look more carefully we find that, as far as the genes are concerned, their destiny is largely shared. The future of the genes in the swarm is, at least to a large extent, lodged in the ovaries of one queen. This is why—it is just another way of expressing the message of earlier chapters—the bee colony looks and behaves like a truly integrated single vehicle.
Richard Dawkins
All life evolves by the differential survival of replicating entities
Richard Dawkins
Evolution is promoted by its practitioners as more than mere science. Evolution is promulgated as an ideology, a secular religion -- a full-fledged alternative to Christianity, with meaning and morality. I am an ardent evolutionist and an ex-Christian, but I must admit that in this one complaint -- and Mr. Gish [Duane T. Gish the Creation Scientist] is but one of many to make it -- the literalists are absolutely right. Evolution is a religion. This was true of evolution in the beginning, and it is true of evolution still today.
Michael Ruse
it is high time we stop using the term “theory” while mentioning Evolution. The term “theory” somehow makes some people think of Evolution as an unproven “hypothesis”. Theory of Evolution is an incontrovertible fact of science. It is not a fictitious story like Creationism. It’s a hard reality. It is the bed-rock of Biology. Defying evolution means defying one’s own existence as a human being.
Abhijit Naskar
Neither humans nor the Gods that they have created are superior to old Mother Nature.
Abhijit Naskar
Evolutionarily speaking, love is all about procreation.
Abhijit Naskar
If you look at the evolution of the brain, the logic centers, they were growing at the same time as the creative centers were expanding. And that creates this really potent illusion that you’re not just a bag of chemicals reacting to shit. Which is what you are.
Tim Cannon
Individual humans are not super, but the organism of which we are all tiny cellular parts is most certainly that. The life-form that's so big we forget it's there, that turns minerals on its planet into tools to touch the infinite black gap between stars or probe the obliterating pressures at the bottom of the oceans. We are already part of a superbeing, a monster, a god, a living process that is so all encompassing that it is to an individual life what water is to a fish. We are cells in the body of a three-billion-year-old life-form whose roots are in the Precambrian oceans and whose genetic wiring extends through the living structures of everything on the planet, connecting everything that has ever lived in one immense nervous system.
Grant Morrison
Considering the way the prebiotic soup is referred to in so many discussions of the origin of life as an already established reality, it comes as something of a shock to realize that there is absolutely no positive evidence for its existence.
Michael Denton
But just in proportion as this process of extermination has acted on an enormous scale, so must the number of intermediate varieties, which have formerly existed, be truly enormous. Why then is not every geological formation and every stratum full of such intermediate links? Geology assuredly does not reveal any such finely graduated organic chain; and this, perhaps, is the most obvious and serious objection which can be urged against the theory. The explanation lies, as I believe, in the extreme imperfection of the geological record.
Charles Darwin
Obsolescence is a fate devoutly to be wished, lest science stagnate and die.
Stephen Jay Gould
I simply would not accede to being forced into this, and would frequently be kept out of classes because of irreverent comments and mocking this religious stuff. Frankly, it stayed with me to this day. In fact, don't get me going. I'm almost as bad as Richard Dawkins on this issue.
Richard E. Leakey
Who gave the decisive deathblow to the argument from design on the basis of biological complexity? Both philosophers and biologists are divided on this point (Oppy 1996; Dawkins 1986; Sober 2008). Some have claimed that the biological design argument did not falter until Darwin provided a proper naturalistic explanation for adaptive complexity; others maintain that David Hume had already shattered the argument to pieces by sheer logical force several decades earlier, in his Dialogues Concerning Natural Religion (Hume 2007 [1779]). Elliott Sober has been among the philosophers who maintain that, as Hume was not in a position to offer a serious alternative explanation of adaptive complexity, it is hardly surprising that 'intelligent people strongly favored the design hypothesis' (Sober 2000, 36). In his most recent book, however, Sober (2008) carefully develops what he thinks is the most charitable reconstruction of the design argument, and proceeds to show why it is defective for intrinsic reasons (for earlier version of this argument, see Sober 1999, 2002). Sober argues that the design argument can be rejected even without the need to consider alternative explanations for adaptive complexity (Sober 2008, 126): 'To see why the design argument is defective, there is no need to have a view as to whether Darwin’s theory of evolution is true' (Sober 2008, 154).
Maarten Boudry
My practice as a scientist is atheistic. That is to say, when I set up an experiment I assume that no god, angel or devil is going to interfere with its course; and this assumption has been justified by such success as I have achieved in my professional career. I should therefore be intellectually dishonest if I were not also atheistic in the affairs of the world.
J.B.S. Haldane
All interpretation or observation of reality is necessarily fiction. In this case, the problem is that man is a moral animal abandoned in an amoral universe and condemned to a finite existence with no other purpose than to perpetuate the natural cycle of the species. It is impossible to survive in a prolonged state of reality, at least for a human being. We spend a good part of our lives dreaming, especially when we're awake. As I said, pure biology.
Carlos Ruiz Zafón
No human, no matter how ancient, or how popular, can be above the laws of Nature.
Abhijit Naskar
I am perhaps more proud of having helped to redeem the character of the cave-man than of any other single achievement of mine in the field of anthropology.
Henry Fairfield Osborn
Stephen Hawking said that his quest is simply "trying to understand the mind of God".
Stephen Hawking
For who could better describe the eye than God, Who made it? But as it is clearer than the day that God has left a good deal to our own efforts ... we should really follow in these things the thread of nature, by which first principles, reason and daily experience lead us. Therefore, He prompts the minds of great men to inquire into the nature which He created, and He furthers and conducts their studies. These things must be enough to us, and from Holy Scripture we should seek in the first place only those things which are necessary to salvation.
Georg Joachim Rheticus
Originally, the atoms of carbon from which we’re made were floating in the air, part of a carbon dioxide molecule. The only way to recruit these carbon atoms for the molecules necessary to support life—the carbohydrates, amino acids, proteins, and lipids—is by means of photosynthesis. Using sunlight as a catalyst the green cells of plants combine carbon atoms taken from the air with water and elements drawn from the soil to form the simple organic compounds that stand at the base of every food chain. It is more than a figure of speech to say that plants create life out of thin air.
Michael Pollan
Advocacy of leaf protein as a human food is based on the undisputed fact that forage crops (such as lucerne) give a greater yield of protein than other types of crops. Even with conventional food crops there is more protein in the leafy parts than in the seeds or tubs that are usually harvested.
Norman Pirie
It is, however, a most astonishing but incontestable fact, that the history of the evolution of man as yet constitutes no part of general education. Indeed, our so-called 'educated classes' are to this day in total ignorance of the most important circumstances and the most remarkable phenomena which Anthropogeny has brought to light.
Ernst Haeckel
One of my friends compared me to Bruce Banner, due to my work with radiation and human health. So I looked up Bruce Banner and this is what I found: Banner, a physicist, is sarcastic and seemingly very self-assured when he first appears in Incredible Hulk #1, but is also emotionally withdrawn in most fashions...Banner is considered one of the greatest scientific minds on Earth, possessing "a mind so brilliant it cannot be measured on any known intelligence test." He holds expertise in biology, chemistry, engineering, physiology, and nuclear physics.
Steven Magee
In AP Bio, I learned that the cells in our body are replaced every seven years, which means that one day, I'll have a body full of cells that were never sick. But it also means that parts of me that knew and loved Sadie will disappear. I'll still remember loving her, but it'll be a different me who loved her. And maybe this is how we move on. We grow new cells to replace the grieving ones, diluting our pain until it loses potency.The percentage of my skin that touched hers will lessen until one day my lips won't be the same lips that kissed hers, and all I'll have are the memories. Memories of cottages in the woods, arranged in a half-moon. Of the tall metal tray return in the dining hall. Of the study tables in the library. The rock where we kissed. The sunken boat in Latham's lake, Sadie, snapping a photograph, laughing the lunch line, lying next to me at the movie night in her green dress, her voice on the phone, her apple-flavored lips on mine. And it's so unfair. All of it.
Robyn Schneider
Science, as long as it limits itself to the descriptive study of the laws of nature, has no moral or ethical quality and this applies to the physical as well as the biological sciences.
Ernst Boris Chain
Perhaps if zoologists would contemplate the wide variations presented by many plants of indubitably one and the same species, and the still wider diversities of long cultivated races from an original stock, they would find more than one instructive parallel to the case of the longest domesticated of all species, man.
Asa Gray
Man is a product of nature, a part of the Universe. The Universe is operated under exact natural laws. Man is a product of millions of years of evolution. He adapts himself to the laws of nature or he perishes.
James Hervey Johnson
No existing form of anthropoid ape is even remotely related to the stock which has given rise to man.
Henry Fairfield Osborn
In microbiology the roles of mutation and selection in evolution are coming to be better understood through the use of bacterial cultures of mutant strains.
Edward Tatum
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