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Information and complexity go hand in hand.
Lee Spetner
My laboratory is interested in the related challenges of understanding the origin of life on the early earth, and constructing synthetic cellular life in the laboratory. Focusing on artificial life frees us to explore novel chemical systems, but what we learn from these systems helps us to understand possible pathways leading to the origin of life. Our basic design for a synthetic cell involves the encapsulation of a spontaneously replicating nucleic acid, which acts as the genetic material, within a spontaneously replicating membrane vesicle, which provides spatial localization. We are using chemical synthesis to make nucleic acids with modified nucleobases and sugar-phosphate backbones.
Jack W. Szostak
The extracellular genesis of cells in animals seemed to me, ever since the publication of the cell theory [of Schwann], just as unlikely as the spontaneous generation of organisms. These doubts produced my observations on the multiplication of blood cells by division in bird and mammalian embryos and on the division of muscle bundles in frog larvae. Since then I have continued these observations in frog larvae, where it is possible to follow the history of tissues back to segmentation.
Robert Remak
There are no mineral monsters.
Canguilhem
A DNA sequence for the genome of bacteriophage ΦX174 of approximately 5,375 nucleotides has been determined using the rapid and simple 'plus and minus' method. The sequence identifies many of the features responsible for the production of the proteins of the nine known genes of the organism, including initiation and termination sites for the proteins and RNAs. Two pairs of genes are coded by the same region of DNA using different reading frames.
Frederick Sanger
It is our alarming misfortune that so primitive a science has armed itself with the most modern and terrible weapons
Rachel Carson
People, as curious primates, dote on concrete objects that can be seen and fondled. God dwells among the details, not in the realm of pure generality. We must tackle and grasp the larger, encompassing themes of our universe, but we make our best approach through small curiosities that rivet our attention - all those pretty pebbles on the shoreline of knowledge. For the ocean of truth washes over the pebbles with every wave, and they rattle and clink with the most wondrous din.
Stephen Jay Gould
Biologists will teach us that the survival of the species depends on cooperation, not competition.
Robert Holden
The virus altered the the eye of the beholder. That this change came at the expense of the beheld suggests that beauty in nature does not necessarily bespeak health, nor necessarily redound to the benefit of the beautiful.
Michael Pollan
Oxygen deprivation and supplemental oxygen are both bio-hazards for Mauna Kea workers
Steven Magee
Biological databases impose particular limitations on how biological objects can be related to one another. In other words, the structure of a database predetermines the sorts of biological relationships that can be 'discovered'. To use the language of Bowker and Star, the database 'torques,' or twists, objects into particular conformations with respect to one another. The creation of a database generates a particular and rigid structure of relationships between biological objects, and these relationships guide biologists in thinking about how living systems work. The evolution of GenBank from flat-file to relational to federated database paralleled biologists' moves from gene-centric to alignment-centric to multielement views of biological action.
Hallam Stevens
Very high altitude astronomy only works by ignoring established biological science
Steven Magee
Water is one of the least understood aspects of biology.
Steven Magee
The attention given to the side of the head which has received the injury, in connection with a specific reference to the side of the body nervously affected, is in itself evidence that in this case the ancient surgeon was already beginning observations on the localization of functions in the brain.
James Henry Breasted
It necessarily follows that chance alone is at the source of every innovation, and of all creation in the biosphere. Pure chance, absolutely free but blind, at the very root of the stupendous edifice of evolution: this central concept of modern biology is no longer one among many other possible or even conceivable hypotheses. It is today the sole conceivable hypothesis, the only one that squares with observed and tested fact. And nothing warrants the supposition - or the hope - that on this score our position is ever likely to be revised. There is no scientific concept, in any of the sciences, more destructive of anthropocentrism than this one.
Jacques Monod
...Why is it, that from the moment you enter medical school to the moment you retire, that the only disorder you will ever diagnosis with a physics book - is obesity? This is biology folks, it's endocrinology, it's physiology - physics has nothing to do with it. The law of thermodynamics is always true, [but] the energy balance equation is irrelevant...
Gary Taubes
I know that certain minds would regard as audacious the idea of relating the laws which preside over the play of our organs to those laws which govern inanimate bodies; but, although novel, this truth is none the less incontestable. To hold that the phenomena of life are entirely distinct from the general phenomena of nature is to commit a grave error, it is to oppose the continued progress of science.
François Magendie
A multitude of harlequin lifeforms bobbed and twirled and played in the depths of the Atlantic. Pink cucumbers with thorny backs. Algae. Starfish. Annelids with simple brains and a hundred toes. Sponges—like yellow, swollen hands—sucked in water and pushed out oxygen. Most amusing were the mysterious buggers who had no likeness on the previous earth; tiny beasts with exotic exoskeletons engraved with deep grid-like patterns, snails with horns, and slithering plants that looked like magenta weeping willows.
Jake Vander-Ark
When I realized that my home was completely filled with a biologically toxic radio wave field, I decided that the best route forward was to milk the home for all of the biological research that I could possibly produce from it!
Steven Magee
Might one not say that in the chance combination of nature's production, since only those endowed with certain relations of suitability could survive, it is no cause for wonder that this suitability is found in all species that exist today? Chance, one might say, produced an innumerable multitude of individuals; a small number turned out to be constructed in such fashion that the parts of the animal could satisfy its needs; in another, infinitely greater number, there was neither suitability nor order: all of the later have perished; animals without a mouth could not live, others lacking organs for reproduction could not perpetuate themselves: the only ones to have remained are those in which were found order and suitability; and these species, which we see today, are only the smallest part of what blind fate produced.
Pierre-Louis Moreau De Maupertuis
When in 1863 Thomas Huxley coined the phrase 'Man's Place in Nature,' it was to name a short collection of his essays applying to man Darwin's theory of evolution. The Origin of Species had been published only four years before, and the thesis that man was literally a part of nature, rather than an earthy vessel charged with some sublimer stuff, was so novel and so offensive to current metaphysics that it needed the most vigorous defense. Half the civilized world was rudely shocked, the other half skeptically amused.Nearly a century has passed since the Origin shattered the complacency of the Victorian world and initiated what may be called the Darwinian revolution, an upheaval of man's ideas comparable to and probably exceeding in significance the revolution that issued from Copernicus's demonstration that the earth moves around the sun. The theory of evolution was but one of many factors contributing to the destruction of the ancient beliefs; it only toppled over what had already been weakened by centuries of decay, rendered suspect by the assaults of many intellectual disciplines; but it marked the beginning of the end of the era of faith.
Homer W. Smith
Natural selection is not the wind which propels the vessel, but the rudder which, by friction, now on this side and now on that, shapes the course.
Asa Gray
The embryological record is almost always abbreviated in accordance with the tendency of nature (to be explained on the principle of survival of the fittest) to attain her needs by the easiest means.
Francis Maitland Balfour
It is not the organs—that is, the character and form of the animal's bodily parts—that have given rise to its habits and particular structures. It is the habits and manner of life and the conditions in which its ancestors lived that have in the course of time fashioned its bodily form, its organs and qualities.
Jean-Baptiste Lamarck
Evolution is an integration of matter and concomitant dissipation of motion during which the matter passes from an indefinite incoherent homogeneity to a definite coherent heterogeneity, and during which the retained motion undergoes a parallel transformation.
Herbert Spencer
Darwin's theory was received in Russia with profound sympathy. While in Western Europe it met firmly established old traditions which it had first to overcome, in Russia its appearance coincided with the awakening of our society after the Crimean War and here it immediately received the status of full citizenship and ever since has enjoyed widespread popularity.
Vladimir Onufrievich Kovalevskiĭ
Living organisms were not independently created, but have descended and diversified over time from common ancestors. And thus, no other biological theory so elegantly explains this. Evolutionary theory has withstood the test of time—by way of vicarious experimentation, observation, analysis, and relentless criticism, though opposing viewpoints still cling to the concept of "design." As a person of the biological sciences, I cannot subscribe to such misguided notions that suggest static biological states. Clearly, proper examination of the natural world reveal evolutionary trajectories—some random, others nonrandom—and all having observable genetic implications. It is only when we apply evolutionary explanations to living systems that it becomes ever so clear. The world was not specifically designed with us in mind, but rather we long since adapted and conformed to our surroundings, only giving it the illusionary appearance of "design.
Tommy Rodriguez
A century ago, people laughed at the notion that we were descended from monkeys. Today, the individuals most offended by that claim are the monkeys.
Jacob M. Appel
I was aware of Darwin's views fourteen years before I adopted them and I have done so solely and entirely from an independent study of the plants themselves.[Letter to W.H. Harvey]
Joseph Dalton Hooker
Every day, hundreds of observations and experiments pour into the hopper of the scientific literature. Many of them don't have much to do with evolution - they're observations about the details of physiology, biochemistry, development, and so on - but many of them do. And every fact that has something to do with evolution confirms its truth. Every fossil that we find, every DNA molecule that we sequence, every organ system that we dissect, supports the idea that species evolved from common ancestors. Despite innumerable possible observations that could prove evolution untrue, we don't have a single one. We don't find mammals in Precambrian rocks, humans in the same layers as dinosaurs, or any other fossils out of evolutionary order. DNA sequencing supports the evolutionary relationships of species originally deduced from the fossil record. And, as natural selection predicts, we find no species with adaptations that only benefit a different species. We do find dead genes and vestigial organs, incomprehensible under the idea of special creation. Despite a million chances to be wrong, evolution always comes up right. That is as close as we can get to a scientific truth.
Jerry A. Coyne
Even today a good many distinguished minds seem unable to accept or even to understand that from a source of noise natural selection alone and unaided could have drawn all the music of the biosphere. In effect natural selection operates upon the products of chance and can feed nowhere else; but it operates in a domain of very demanding conditions, and from this domain chance is barred. It is not to chance but to these conditions that evolution owes its generally progressive course, its successive conquests, and the impression it gives of a smooth and steady unfolding.
Jacques Monod
Who gave the decisive deathblow to the argument from design on the basis of biological complexity? Both philosophers and biologists are divided on this point (Oppy 1996; Dawkins 1986; Sober 2008). Some have claimed that the biological design argument did not falter until Darwin provided a proper naturalistic explanation for adaptive complexity; others maintain that David Hume had already shattered the argument to pieces by sheer logical force several decades earlier, in his Dialogues Concerning Natural Religion (Hume 2007 [1779]). Elliott Sober has been among the philosophers who maintain that, as Hume was not in a position to offer a serious alternative explanation of adaptive complexity, it is hardly surprising that 'intelligent people strongly favored the design hypothesis' (Sober 2000, 36). In his most recent book, however, Sober (2008) carefully develops what he thinks is the most charitable reconstruction of the design argument, and proceeds to show why it is defective for intrinsic reasons (for earlier version of this argument, see Sober 1999, 2002). Sober argues that the design argument can be rejected even without the need to consider alternative explanations for adaptive complexity (Sober 2008, 126): 'To see why the design argument is defective, there is no need to have a view as to whether Darwin’s theory of evolution is true' (Sober 2008, 154).
Maarten Boudry
Man is a product of nature, a part of the Universe. The Universe is operated under exact natural laws. Man is a product of millions of years of evolution. He adapts himself to the laws of nature or he perishes.
James Hervey Johnson
If a single cell, under appropriate conditions, becomes a man in the space of a few years, there can surely be no difficulty in understanding how, under appropriate conditions, a cell may, in the course of untold millions of years, give origin to the human race.
Herbert Spencer
Not only in antiquity but in our own times also laws have been passed...to secure good conditions for workers; so it is right that the art of medicine should contribute its portion for the benefit and relief of those for whom the law has shown such foresight...[We] ought to show peculiar zeal...in taking precautions for their safety. I for one have done all that lay in my power, and have not thought it beneath me to step into workshops of the meaner sort now and again and study the obscure operations of mechanical arts.
Bernardino Ramazzini
She had a theory that the fear of getting in trouble was what made her not as good a programmer and that, in fact, it was all linked to testosterone, and that was why there were more guy programmers than women. It was a very hazy theory, and she didn't like it, but she had pretty much convinced herself it was true, although she couldn't bear to think of sharing it with anybody, because it was a lot better to think that there were social reasons why girls didn't usually become code monkeys than to think there were biological reasons.
Maureen F. McHugh
Wherever sufficiently numerous series of the remains of any given group, which has endured for a long space of time, are carefully examined, their morphological relations are never in discordance with the requirements of the doctrine of evolution, and often afford convincing evidence of it. At the same time, it has been shown that certain forms persist with very little change, from the oldest to the newest fossiliferous formations; and thus show that progressive development is a contingent, and not a necessary result, of the nature of living matter.
Thomas Henry Huxley
I told my three sons stories about germs more than fifty years ago as fanciful bedtime tales.
Arthur Kornberg
When I am fully immersed in my work of nourishing humanity, it fills my head with all kinds of feel-good chemicals, such as endorphins, serotonin and dopamine. Problems occur during the brief intervals between the finishing of one work and the beginning of another. During these intervals, my biology starts to get filled with stress hormones cortisol and adrenalin, that worsens my OCD. That is why, I can’t sit still even a day after I finish writing a book. Because if I do, my OCD begins to suffocate me inside my head. Hence, as soon as I deliver a work, I have to start working on my next scientific literature.
Abhijit Naskar
When Mother Nature speaks, even the Gods hold silence.
Abhijit Naskar
We biologists often use the phrase “Mother Nature” to refer to the entire system of Nature that we see around us, but it is not really an entity, and it does not have any real concern for any of its living creatures – it lives on with or without us; it is in our human psychology to impose a human-like identity upon any grand system that we encounter around us – it gives us a sense of closeness to that system and makes us feel an essential part of it. When I say, Mother Nature designed us, or programmed us, I am simply referring to the process of natural selection.
Abhijit Naskar
The race is now on between the technoscientific and scientific forces that are destroying the living environment and those that can be harnessed to save it. . . . If the race is won, humanity can emerge in far better condition than when it entered, and with most of the diversity of life still intact.
Edward O. Wilson
I wanted to present Neuroscience to people in a way that would diminish their differences.
Abhijit Naskar
Sorgan tried his very best not to think about how long it must have taken for a stream that small to eat its way down through solid rock to form its current bed. Sorgan knew exactly what the word “hundred” meant, but when numbers wandered off toward “thousand”—or even “million”—and the people who used those terms were talking about years, Sorgan’s mind shied back in horror.
David Eddings
I don't believe any scientific field to be superior to another.
Abhijit Naskar
Quick dinner with ... Ang [Lee] and his wife Jane who's visiting with the children for a while. We talked about her work as a microbiologist and the behaviour of the epithingalingie under the influence of cholesterol. She's fascinated by cholesterol. Says it's very beautiful: bright yellow. She says Ang is wholly uninterested. He has no idea what she does.I check this out for myself. 'What does Jane do?' I ask.'Science,' he says vaguely.
Emma Thompson
I like to define biology as the history of the earth and all its life — past, present, and future. To understand biology is to understand that all life is linked to the earth from which it came; it is to understand that the stream of life, flowing out of the dim past into the uncertain future, is in reality a unified force, though composed of an infinite number and variety of separate lives.
Rachel Carson
The information contained in an English sentence or computer software does not derive from the chemistry of the ink or the physics of magnetism, but from a source extrinsic to physics and chemistry altogether. Indeed, in both cases, the message transcends the properties of the medium. The information in DNA also transcends the properties of its material medium.
Stephen C. Meyer
Molecular biology has shown that even the simplest of all living systems on the earth today, bacterial cells, are exceedingly complex objects. Although the tiniest bacterial cells are incredibly small, weighing less than 10-12 gms, each is in effect a veritable micro-miniaturized factory containing thousands of exquisitely designed pieces of intricate molecular machinery, made up altogether of one hundred thousand million atoms, far more complicated than any machine built by man and absolutely without parallel in the nonliving world.
Michael Denton
To grasp the reality of life as it has been revealed by molecular biology, we must magnify a cell a thousand million times until it is twenty kilometers in diameter and resembles a giant airship large enough to cover a great city like London or New York. What we would then see would be an object of unparalleled complexity and adaptive design. On the surface of the cell we would see millions of openings, like the port holes of a vast space ship, opening and closing to allow a continual stream of materials to flow in and out. If we were to enter one of these openings we would find ourselves in a world of supreme technology and bewildering complexity.
Michael Denton
To establish evolutionary interrelatedness invariably requires exhibiting similarities between organisms. Within Darwinism, there's only one way to connect such similarities, and that's through descent with modification driven by the Darwinian mechanism. But within a design-theoretic framework, this possibility, though not precluded, is also not the only game in town. It's possible for descent with modification instead to be driven by telic processes inherent in nature (and thus by a form of design). Alternatively, it's possible that the similarities are not due to descent at all but result from a similarity of conception, just as designed objects like your TV, radio, and computer share common components because designers frequently recycle ideas and parts. Teasing apart the effects of intelligent and natural causation is one of the key questions confronting a design-theoretic research program. Unlike Darwinism, therefore, intelligent design has no immediate and easy answer to the question of common descent.Darwinists necessarily see this as a bad thing and as a regression to ignorance. From the design theorists' perspective, however, frank admissions of ignorance are much to be preferred to overconfident claims to knowledge that in the end cannot be adequately justified. Despite advertisements to the contrary, science is not a juggernaut that relentlessly pushes back the frontiers of knowledge. Rather, science is an interconnected web of theoretical and factual claims about the world that are constantly being revised and for which changes in one portion of the web can induce radical changes in another. In particular, science regularly confronts the problem of having to retract claims that it once confidently asserted.
William A. Dembski
The complexity of the simplest known type of cell is so great that it is impossible to accept that such an object could have been thrown together suddenly by some kind of freakish, vastly improbable, event. Such an occurrence would be indistinguishable from a miracle.
Michael Denton
If Darwinists are opposed to mentioning scientific problems with their view, you would think they would be even more opposed to mentioning intelligent design. Yet Darwinists have been discussing ID in public school science classes for years... Biology textbooks have been mentioning intelligent design since the late 1990s—but only to misrepresent and disparage it.
Jonathan Wells
The phrase 'the fossil record' sounds impressive and authoritative. As used by some persons it becomes, as intended, intimidating, taking on the aura of esoteric truth as expounded by an elite class of specialists. But what is it, really, this fossil record? Only data in search of interpretation. All claims to the contrary that I know, and I know of several, are so much superstition.
Gareth J. Nelson
The most essential prediction of Darwinism is that, given an astronomical number of chances, unintelligent processes can make seemingly-designed systems, ones of the complexity of those found in the cell. ID specifically denies this, predicting that in the absence of intelligent input no such systems would develop. So Darwinism and ID make clear, opposite predictions of what we should find when we examine genetic results from a stupendous number of organisms that are under relentless pressure from natural selection. The recent genetic results are a stringent test. The results: 1) Darwinism’s prediction is falsified; 2) Design’s prediction is confirmed.
Michael J. Behe
Sorgan tried his very best not to think about how long it must have taken for a stream that small to eat its way down through solid rock to form its current bed. Sorgan knew exactly what the word “hundred” meant, but when numbers wandered off toward “thousand”—or even “million”—and the people who used those terms were talking about years, Sorgan’s mind shied back in horror.
David Eddings
I don't believe any scientific field to be superior to another.
Abhijit Naskar
Now you know that the fascinating phenomenon of love has nothing to do with the supernatural entity known as Cupid, but everything to do with neurochemistry. Likewise, divinity is a cerebral creation, not a supernatural one. And it has been long since thinking humanity has learnt that love is a majestic creation of the brain, yet that knowledge hasn’t made love be deemed any less glorious. Then why should it threaten the religious believer to learn that divinity as well is a natural creation of the brain!
Abhijit Naskar
Quick dinner with ... Ang [Lee] and his wife Jane who's visiting with the children for a while. We talked about her work as a microbiologist and the behaviour of the epithingalingie under the influence of cholesterol. She's fascinated by cholesterol. Says it's very beautiful: bright yellow. She says Ang is wholly uninterested. He has no idea what she does.I check this out for myself. 'What does Jane do?' I ask.'Science,' he says vaguely.
Emma Thompson
Molecular machines display a key signature or hallmark of design, namely, irreducible complexity. In all irreducibly complex systems in which the cause of the system is known by experience or observation, intelligent design or engineering played a role in the origin of the system... We find such systems within living organisms.
Scott A. Minnich
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