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When people have trouble with their emotions – a bout of anxiety or depression, say, or seasonal gloominess – they often want science to pinpoint an offending neurotransmitter in the way that a witness picks the perp out of a lineup. Is it excessive norepinephrine, too little dopamine, errant estrogen? The answer is apt to dissatisfy: no single suspect can be fingered with confidence because the question itself attributes a fallacious simplicity to the brain.(91)