Quotes by Physicians - Page 127

Why would you take a drug that is guaranteed to kill you in forty years? One reason, right? It's the only thing that will stop you dying tomorrow.
Sharon Moalem
The capacity to blunder slightly is the real marvel of DNA. Without this special attribute, we would still be anaerobic bacteria and there would be no music.
Lewis Thomas
Science is a first-rate piece of furniture for a man's upper chamber, if he has common sense on the ground floor.
Oliver Wendell Holmes Sr.
Science is the topography of ignorance.
Oliver Wendell Holmes Sr.
Science without conscience is the soul's perdition.
François Rabelais
You are a placebo responder. Your body plays tricks on your mind. You cannot be trusted.
Ben Goldacre
It is not my intention to be fulsome, but I confess that I covet your skull.
Arthur Conan Doyle
Science, like life, feeds on its own decay. New facts burst old rules; then newly divined conceptions bind old and new together into a reconciling law.
William James
It is a capital mistake to theorise before one has data.
Arthur Conan Doyle
It is very expensive to give bad medical care to poor people in a rich country.
Paul Farmer
As to diseases, make a habit of two things — to help, or at least, to do no harm.
Hippocrates
I may not always be right, but when I am, I admit it
Ken Murray
There is nothing more awful, insulting, and depressing than banality.
Anton Chekhov
Most of the things that give life its depth, meaning, and value are impervious to science.
Rachel Naomi Remen
Medicine is as close to love as it is to science, and its relationships matter even at the edge of life itself.
Rachel Naomi Remen
In metric, one milliliter of water occupies one cubic centimeter, weighs one gram, and requires one calorie of energy to heat up by one degree centigrade—which is 1 percent of the difference between its freezing point and its boiling point. An amount of hydrogen weighing the same amount has exactly one mole of atoms in it. Whereas in the American system, the answer to ‘How much energy does it take to boil a room-temperature gallon of water?’ is ‘Go fuck yourself,’ because you can’t directly relate any of those quantities.
Josh Bazell
In whatever disease sleep is laborious, it is a deadly symptom; but if sleep does good, it is not deadly.
Hippocrates
Not all social animals are social with the same degree of commitment. In some species, the members are so tied to each other and interdependent as to seem the loosely conjoined cells of a tissue. The social insects are like this; they move, and live all their lives, in a mass; a beehive is a spherical animal. In other species, less compulsively social, the members make their homes together, pool resources, travel in packs or schools, and share the food, but any single one can survive solitary, detached from the rest. Others are social only in the sense of being more or less congenial, meeting from time to time in committees, using social gatherings as ad hoc occasions for feeding and breeding. Some animals simply nod at each other in passing, never reaching even a first-name relationship.
Lewis Thomas
[Hegel’s] system of nature seemed, at least to natural philosophers, absolutely crazy….Hegel…launched out with particular vehemence and acrimony against the natural philosophers, and especially against Isaac Newton. The philosophers accused the scientific men of narrowness; the scientific men retorted that the philosophers were insane.
Hermann von Helmholtz
The individual parts played by other instrumentalists-- crickets or earthworms, for instance-- may not have the sound of music by themselves, but we hear them out of context. If we could listen to them all at once, fully orchestrated, in their immense ensemble, we might become aware of the counterpoint, the balance of tones and timbres and harmonics, the sonorities. The recorded songs of the humpback whale, filled with tensions and resolutions, ambiguities and allusions, incomplete, can be listened to as a a part of music, like an isolated section of an orchestra. If we had better hearing, we could discern the descants of sea birds, the rhythmic tympani of schools of mollusks, or even the distant harmonies of midges hanging over meadows in the sun, the combined sound might lift us off our feet.
Lewis Thomas
Working on a typewriter by touch, like riding a bicycle or strolling on a path, is best done by not giving it a glancing thought. Once you do, your fingers fumble and hit the wrong keys. To do things involving practiced skills, you need to turn loose the systems of muscles and nerves responsible for each maneuver, place them on their own, and stay out of it. There is no real loss of authority in this, since you get to decide whether to do the thing or not, and you can intervene and embellish the technique any time you like; if you want to ride a bicycle backward, or walk with an eccentric loping gait giving a little skip every fourth step, whistling at the same time, you can do that. But if you concentrate your attention on the details, keeping in touch with each muscle, thrusting yourself into a free fall with each step and catching yourself at the last moment by sticking out the other foot in time to break the fall, you will end up immobilized, vibrating with fatigue. It is a blessing to have options for choice and change in the learning of such unconsciously coordinated acts. If we were born with all these knacks inbuilt, automated like ants, we would surely miss the variety. It would be a less interesting world if we all walked and skipped alike, and never fell from bicycles. If we were all genetically programmed to play the piano deftly from birth, we might never learn to understand music.
Lewis Thomas
It is not a simple thing to decide where we fit, for at one time or another in our lives we manage to organize in every imaginable social arrangement...We have names to label each as self, and we believe without reservation that this system of taxonomy will guarantee the entity, the absolute separateness in each of us, but the mechanism has no discernible function in the center of a crowded city; we are essentially nameless, most of our time.
Lewis Thomas
Perhaps it is in this respect that language differs most sharply from other biologic systems for communication. Ambiguity seems to be an essential, indispensable element for the transfer of information from one place to another by words, where matters of real importance are concerned. It is often necessary, for meaning to come through, that there be an almost vague sense of strangeness and askewness. Speechless animals and cells cannot do this. The specifically locked-on antigen at the surface of a lymphocyte does not send the cell off in search of something totally different; when a bee is tracking sugar by polarized light, observing the sun as though consulting his watch, he does not veer away to discover an unimaginable marvel of a flower. Only the human mind is designed to work in this way, programmed to drift away in the presence of locked-on information, straying from each point in a hunt for a better, different point.If it were not for the capacity for ambiguity, for the sensing of strangeness, the words in all languages provide, we would have no way of recognizing the layers of counterpoint in meaning, and we might be spending all our time sitting on stone fences, staring into the sun. To be sure, we would always have had some everyday use to make of the alphabet, and we might have reached the same capacity for small talk, but it is unlikely that we would have been able to evolve from words to Bach. The great thing about human language is that it prevents us from sticking to the matter at hand.
Lewis Thomas
It is in our collective behavior that we are the most mysterious. We won't be able to construct machines like ourselves until we've understood this, and we're not even close. All we know is the phenomenon: we spend our time sending messages to each other, talking and trying to listen at the same time, exchanging information. This seems to be our most urgent biological function; it is what we do with our lives. By the time we reach the end, each of us has taken in a staggering store, enough to exhaust any computer, much of it incomprehensible, and we generally manage to put out even more than we take in. Information is our source of energy; we are driven by it. It has become a tremendous enterprise, a kind of energy system on its own. All 3 billion of us are being connected by telephones, radios, television sets, airplanes, satellites, harangues on public-address systems, newspapers, magazines, leaflets dropped from great heights, words got in edgewise. We are becoming a grid, a circuitry around the earth.
Lewis Thomas
However, I have a stronger hunch that the greatest part of the important biomedical research waiting to be done is in the class of basic science. There is an abundance of interesting fact relating to all our major diseases, and more items of information are coming in steadily from all quarters in biology. The new mass of knowledge is still formless, in complete, lacking the essential threads of connection, displaying misleading signals at every turn, riddled with blind alleys. There are fascinating ideas all over the place, irresistible experiments beyond numbering, all sorts of new ways into the maze of problems. But every next move is unpredictable, every outcome uncertain. It is a puzzling time, but a very good time. I do not know how you lay out orderly plans for this kind of activity, but I suppose you could find out by looking through the disorderly records of the past hundred years. Somehow, the atmosphere has to be set so that a disquieting sense of being wrong is the normal attitude of the investigators. It has to be taken for granted that the only way in is by riding the unencumbered human imagination, with the special rigor required for recognizing that something can be highly improbable, maybe almost impossible, and at the same time true.Locally, a good way to tell how the work is going is to listen in the corridors. If you hear the word, "Impossible!" spoken as an expletive, followed by laughter, you will know that someone's orderly research plan is coming along nicely.
Lewis Thomas
Statistically, the probability of any one of us being here is so small that you'd think the mere fact of existing would keep us all in a contented dazzlement of surprise. We are alive against the stupendous odds of genetics, infinitely outnumbered by all the alternates who might, except for luck, be in our places.Even more astounding is our statistical improbability in physical terms. The normal, predictable state of matter throughout the universe is randomness, a relaxed sort of equilibrium, with atoms and their particles scattered around in an amorphous muddle. We, in brilliant contrast, are completely organized structures, squirming with information at every covalent bond. We make our living by catching electrons at the moment of their excitement by solar photons, swiping the energy released at the instant of each jump and storing it up in intricate loops fro ourselves. We violate probability, by our nature. To be able to do this systematically, and in such wild varieties of form, from viruses to whales, is extremely unlikely; to have sustained the effort successfully for the several billion years of our existence, without drifting back into randomness, was nearly a mathematical impossibility. Add to this the biological improbability that makes each member of our own species unique. Everyone is one in 3 billion at the moment, which describes the odds. Each of us is a self-contained, free-standing individual, labeled by specific protein configurations at the surfaces of cells, identifiable by whorls of fingertip skin, maybe even by special medleys of fragrance. You'd think we'd never stop dancing.
Lewis Thomas
It is hard to feel affection for something as totally impersonal as the atmosphere, and yet there it is, as much a part and product of life as wine and bread. Taken all in al, the sky is a miraculous achievement. It works, and for what it is designed to accomplish it is as infallible as anything in nature. I doubt whether any of us could think of a way to improve on it, beyond maybe shifting a local cloud from here to there on occasion. The word 'chance' does not serve to account well for structures of such magnificence...We should credit it for what it is: for sheer size and perfection of function, it is far and away the grandest product of collaboration in all of nature.It breathes for us, and it does another thing for our pleasure. Each day, millions of meteorites fall against the outer limits of the membrane and are burned to nothing by the friction. Without this shelter, our surface would long since have become the pounded powder of the moon. Even though our receptors are not sensitive enough to hear it, there is comfort in knowing the sound is there overhead, like the random noise of rain on the roof at night.
Lewis Thomas
When power is discovered, man always turns to it," Bateson wrote darkly. "The science of heredity will soon provide power on stupendous scale; and in some country, at some time not, perhaps, far distant, that power will be applied to control the composition of a nation. Whether the institution of such control will ultimately be good or bad for that nation, or humanity at large, is a separate question." He had preempted the century of the gene.
Siddharta Mukherjee
Phenotype, in short, drags genotypes behind it, like a cart pulling a horse. It is the perennial conundrum of natural selection that it seeks one thing (fitness) and accidentally finds another (genes that produce fitness). Genes that produce fitness become gradually over-represented in populations through the selection phenotypes, thereby allowing organisms to become more and more adapted to their environments. There is no such thing as perfection, only the relentless, thirsty matching of an organism to its environment. That is the engine that drives evolution.
Siddharta Mukherjee
This was the missing link in Darwin's Logic: reproductive incompatibility, ultimately derived from genetic incompatibility, drove the origin of novel species.
Siddharta Mukherjee
Muller was catapulted into the international fame by his discovery. The effect of radiation on the mutation rate in flies had two immediate implications. First, genes had to be made of matter. Radiation, after all, is merely energy. Frederick Griffith had made genes move between organisms. Muller had altered genes using energy. A gene, whatever it was, was capable of motion, transmission, and of energy-induced change properties generally associated with chemical matter.
Siddharta Mukherjee
It isn't creativity that fades, but stamina: science is an endurance sport
Siddharta Mukherjee
Gene, protein, function, and fate were strung in a chain: one chemical alteration in one base pair in DNA was sufficient to "encode" a radical change in human fate.
Siddharta Mukherjee
The cheese-mites asked how the cheese got there, And warmly debated the matter; The Orthodox said that it came from the air, And the Heretics said from the platter. They argued it long and they argued it strong, And I hear they are arguing now; But of all the choice spirits who lived in the cheese, Not one of them thought of a cow.
Arthur Conan Doyle
As the geneticist J.B.S. Haldane had described it in 1923, once the power to control genes had been harnessed, "no beliefs, no values, no institutions are safe.
Siddharta Mukherjee
The rediscovery of Mendel's laws of heredity in the opening weeks of the 20th century sparked a scientific quest to understand the nature and content of genetic information that has propelled biology for the last hundred years. The scientific progress made [since that time] falls naturally into four main phases, corresponding roughly to the four quarters of the century.""The first established the cellular basis of heredity: the chromosomes. The second defined the molecular basis of heredity: the DNA double helix. The third unlocked the informational basis of heredity [i.e. the genetic code], with the discovery of the biological mechanism by which cells read the information contained in genes, and with the invention of the recombinant DNA technologies of cloning and sequencing by which scientists can do the same." The sequence of the human genome, the project asserted, marked the starting point of the "fourth phase" of genetics. This was the era of "genomics" - the assessment of the entire genomes of organisms, including humans. There is an old conundrum in philosophy that asks if an intelligent machine can ever decipher its own instruction manual. For humans, the manual was now complete. Deciphering it, reading it, and understanding it would be quite another matter.
Siddharta Mukherjee
Some may smile and may feel that this is but a new version of the old dream of the perfection of man. It is that, but it is something more. The old dreams of the cultural perfections of man were always sharply constrained by his inherent, inherited imperfections and limitations... We now glimpse another route - the chance to ease and consciously perfect beyond our present vision this remarkable product of two billion years of evolution.
Siddharta Mukherjee
For the elements have the property of moving back to their place in a straight line, but they have no properties which would cause them to remain where they are, or to move other-wise than in a straight line, These rectilinear motions of these four elements when returning to their original place are are of two kinds, either centrifugal,vziz.>the motion of the air and the fire; or centripedal,viz.> the motion of the earth, and the water; and when the elements have reached their original place, they remain at rest.
Maimonides
Doctrine once sown strikes deep its root, and respect for antiquity influences all men.
William Harvey
never forget that it is not a pneumonia, but pneumonic man who is your patient
William Withey Gull
Science and art,... they seek the truth and the meaning of life, they seek God, [and] the soul, and when they are harnessed to passing needs and activities,... then they only complicate and encumber life.
Anton Chekhov
Let us begin by giving all proper respect to what neuroscience can tell us about ourselves: it reveals some of the most important conditions that are necessary for behavior and awareness. What neuroscience does not do, however, is provide a satisfactory account of the conditions that are sufficient for behavior and awareness. ... The pervasive yet mistaken idea that neuroscience does fully account for awareness and behavior is neuroscientism, an exercise in science-based faith. ... This confusion between necessary and sufficient conditions lies behind the encroachment of “neuroscientistic” discourse on academic work in the humanities...
Raymond Tallis
The greatest single achievement of nature to date was surely the invention of the molecule DNA.
Lewis Thomas
The heart of animals is the foundation of their life, the sovereign of everything within them, the sun of their microcosm, that upon which all growth depends, from which all power proceeds.
William Harvey
Homeopathy pills are, after all, empty little sugar pills which seem to work, and so they embody [..] how we can be misled into thinking that any intervention is more effective than it really is.
Ben Goldacre
Natural,my ass! The worst poison known to man comes from a tree frog in South America. You cannot imagine how small an amount would be necessary to kill you.and it's natural.Calling something NATURAL is a MEANINGLESS MARKETING PLOY.""All right,calm down! Maybe I like alternative medicine because it's been in use for more than six thousand years.After all that time,they have to know what they're doing.""You mean the wacky idea that somehow in the distant past people had more scientific wisdom than they do today?That's both crazy and counterintuitive.Six thousand years ago people thought thunder was a bunch of gods moving around furniture."-Conversation btw Dr.Jack Stapleton and Vinnie
Robin Cook
Birth after birth the line unchanging runs,And fathers live transmitted in their sons;Each passing year beholds the unvarying kinds,The same their manners, and the same their minds:Till, as erelong successive buds decay,And insect-shoals successive pass away,Increasing wants the pregnant parent vexWith the fond wish to form a softer sex. ..
Erasmus Darwin
I think you'll find it's a bit more complicated than that.
Ben Goldacre
And if, by the end [of this book], you reckon you might still disagree with me, then I offer you this: you'll still be wrong, but you'll be wrong with a lot more panache and flair than you could possibly manage right now.
Ben Goldacre
Round about the accredited and orderly facts of every science there ever floats a sort of dust-cloud of exceptional observations, of occurrences minute and irregular and seldom met with, which it always proves more easy to ignore than to attend to... Anyone will renovate his science who will steadily look after the irregular phenomena, and when science is renewed, its new formulas often have more of the voice of the exceptions in them than of what were supposed to be the rules.
William James
Health is normal. The human body is a self-repairing, self-defending, self-healing marvel. Disease is relatively difficult to induce, considering the body's powerful immune system. However, this complicated and delicate machinery can be damaged if fed the wrong fuel during the formative years. ... Healthy living with nutritional excellence throughout life can slow the decline of aging. It can prevent the years and years of suffering in ill health that is so common today as people get older and become dependent on medical treatments, drugs, and surgery. Nutritional excellence is the only real fountain of youth.
Joel Fuhrman
I am a member of a fragile species, still new to the earth, the youngest creatures of any scale, here only a few moments as evolutionary time is measured, a juvenile species, a child of a species. We are only tentatively set in place, error prone, at risk of fumbling, in real danger at the moment of leaving behind only a thin layer of of our fossils, radioactive at that.
Lewis Thomas
To a naturalist nothing is indifferent; the humble moss that creeps upon the stone is equally interesting as the lofty pine which so beautifully adorns the valley or the mountain: but to a naturalist who is reading in the face of the rocks the annals of a former world, the mossy covering which obstructs his view, and renders indistinguishable the different species of stone, is no less than a serious subject of regret.
James Hutton
Why would you take a drug that is guaranteed to kill you in forty years? One reason, right? It's the only thing that will stop you dying tomorrow.
Sharon Moalem
The capacity to blunder slightly is the real marvel of DNA. Without this special attribute, we would still be anaerobic bacteria and there would be no music.
Lewis Thomas
Science is a first-rate piece of furniture for a man's upper chamber, if he has common sense on the ground floor.
Oliver Wendell Holmes Sr.
Science is the topography of ignorance.
Oliver Wendell Holmes Sr.
Science without conscience is the soul's perdition.
François Rabelais
You are a placebo responder. Your body plays tricks on your mind. You cannot be trusted.
Ben Goldacre
It is not my intention to be fulsome, but I confess that I covet your skull.
Arthur Conan Doyle